Glucocorticoid Response Network

The lab’s main project integrates many molecular genomics assays (ChIP-seq, PRO-seq, ATAC-seq, ChIA-PET, and PB-seq) to reveal regulatory networks. The key to understanding regulatory networks is to assay molecular events at high temporal resolution. We have chosen many time points after glucocorticoid treatment to measure molecular events, such as nascent transcription, chromatin changes, chromosome looping, and protein binding in leukemia cells.